Research Support

Yorkshire Ambulance Service NHS Trust supports participation in research related to our services. We work with the pharmaceutical industry, Universities, and NHS partner organisations, including the National Institute for Health Research Clinical Research Network.

We have a team who can advise and support researchers, and make sure that research complies with any relevant laws and policies. We encourage you to contact us as early as possible to discuss your project. Contact the Research and Development Department on 01924 584027 or via email at

Details of each year's research activity and publications are published annually in the trust's Quality Account.

Recently Completed Research

RIGHT—2: Rapid Intervention with Glyceryl Trinitrate in Hypertensive stroke Trial-2 (RIGHT2): Assessment of safety and efficacy of transdermal glyceryl trinitrate, a nitric oxide donor, and of the feasibility of a multi-centre ambulance-based stroke trial

YAS is supporting this British Heart Foundation funded clinical trial on treating stroke, which will run until May 2018. This study is sponsored by the University of Nottingham.
Connected Health Cities: Data linkage of urgent care data YAS is one of the NHS organisations participating in this Northern Health Science Alliance funded study. This is sponsored by Sheffield Teaching Hospitals NHS Trust.
Yorkshire Health Study This is a long-term Yorkshire-wide University of Sheffield-sponsored health study aims to help build a fit and healthy Yorkshire.
Mindshine3: A definitive randomised controlled trial investigating two online wellbeing interventions to reduce NHS staff stress YAS is participating in this staff wellbeing study which is funded by the Economic and Social Research Council and sponsored by the University of Sussex.

Current Research

MATTS: Major Trauma Triage Tool Study This study aims to develop accurate, acceptable and usable pre-hospital triage tools for use in NHS trauma networks. This will effectively identify patients with the potential to benefit from major trauma centre (MTC) care and optimise over and under-triage
Breathlessness Relief at Home (BREATHE) This study aims to evaluate the effectiveness and cost-effectiveness of a paramedic-administered breathlessness crisis intervention for people with acute-on-chronic breathlessness compared with usual care.
Safety Index of Pre-hospital On-scene Triage (SINEPOST) This is a PhD data study which aims to use ambulance service clinical data to predict avoidable attendance at the emergency department (ED).


Please see the YAS Privacy Policy page for further information: Privacy Policy



The data being used in this study is Ambulance Service and Emergency Department (Accident and Emergency) data.  If you contacted one of these services between Monday 1 July 2019 and Friday 28 February 2020, your data is likely to be included.  If you would not like your data included, please email with your name and date of contact. This is confidential and secure and there will be no repercussions from doing so. Withdrawing your data from the study does not preclude you from further studies. Please see the SINEPOST study privacy notice for further information. 

COVID-19 related research

Pandemic Respiratory Infection Emergency System Triage (PRIEST)

YAS will be participating in a new study to help predict serious coronavirus cases

The study, led by Professor Steve Goodacre from the University’s School of Health and Related Research (ScHARR) and sponsored by Sheffield Teaching Hospitals NHS Trust, aims to optimise how patients with coronavirus are assessed and treated by the emergency care system in the current pandemic.

YAS will work with the study team and other participating hospital emergency departments (EDs) to understand which patients with coronavirus are likely to develop serious illness and therefore need to be admitted to hospital.

Results could help to identify the most accurate triage methods for predicting serious illness among patients with suspected coronavirus or develop new methods that are more accurate than the systems currently used.

The research will evaluate the triage methods used at Yorkshire Ambulance Service through NHS 111 and 999 calls and in face-to-face ambulance callouts

This is to determine whether a patient with a suspected case of coronavirus should be admitted to hospital or not and looks to develop new methods of triage.

The results of the study may also be able to help identify which patient characteristics are associated with a higher risk of serious complications such as age or underlying health conditions.

This study is one of a number of COVID-19 studies that have been given urgent public health research status by the Chief Medical Officer and Deputy Chief Medical Officer for England.

The project is funded by the National Institute for Health Research Health Technology Assessment (NIHR HTA) Programme - project number 11/46/07. Any views or opinions expressed are those of the authors and do not necessarily reflect those of the HTA programme, NIHR, NHS or the Department of Health.

For more information on the PRIEST study, including details of patient confidentiality and how patients can opt to have their information removed from the project, visit the University of Sheffield website.

We also support our staff and external students who want to undertake research as part of post-graduate study.

For health research we may use anonymised data and all NHS research is approved by a group of ethics experts before being carried out. You can find out more information about your rights here:

Research study TRIM

This patient notification contains information about the research study TRIM which is looking at how ambulance services responded to 999 calls for suspected COVID-19.

YAS Performance

Performance in initiating and delivering clinical research - national targets for research

The Government wishes to see a dramatic and sustained improvement in the performance of providers of NHS services in initiating and delivering clinical research with the aim to increase the number of patients who have the opportunity to participate in research. Here you will find our most recent quarterly reports to the Department of Health under the ‘Performance in initiating and delivering clinical research initiative’.

The Trust’s clinical trial performance is measured against two national benchmarks to improve the initiation and delivery of all clinical trials approved by the Trust.

  • Initiation – it should take no more than 70 days from receipt of valid research application to the recruitment of the first patient to the trial.
  • Delivery – for all commercial clinical trials hosted by the Trust, the agreed number of patients should be recruited within the agreed timescale.

The latest performance information for the Trust is available on the NIHR website.

For further information regarding this please contact the Research and Development Department on 01924 584027 or via email at